The most commonly used drug for syphilis treatment is penicillin, including ordinary water penicillin, procaine penicillin and long-acting penicillin, no matter which kind of penicillin, it is necessary to do penicillin skin test first, and only if the skin test is negative can it be used, if the skin test is positive it cannot be used. 1, long-acting penicillin is the simplest one inside these kinds of penicillin to use, the usual treatment plan is 2.4 million units, injected once a week. It is very painful when injecting this drug, so you must be psychologically prepared if you treat it. 2. Procaine penicillin is injected once a day, but this drug is not available in many hospitals now. 3. Aqueous penicillin, the most common penicillin, is also very good, but this drug is more troublesome to use, usually 4 or 6 hours to use The majority of cases require hospitalization to use.