Gallstones are a common and frequent disease, it includes gallbladder stones, intrahepatic bile duct, common bile duct stones, it is also called cholelithiasis. Gallstones are generally associated with dysfunction of the neuroendocrine system, imbalance of bile ratio, and biliary tract infection. In daily life, gallstones can be caused by the following factors: long-term consumption of foods high in sugar and fat and cholesterol, irregular meals, long-term fasting for lack of nutrition, and infection caused by roundworms entering the bile duct. Gallstones are most common in people who have a family history of gallstones, elderly people aged 50-80, people who eat too much fatty food, people who eat too many sweets, people who skip breakfast for a long time, and people who are too obese. Common factors that trigger gallbladder stones are 1, long-term high protein, high fat, high calorie diet increases cholesterol in the body, resulting in cholesterol supersaturation in the bile. 2, certain intestinal diseases due to the loss of bile salts, also make cholesterol in a relatively oversaturated state. 3.Inability to eat on time, bile is retained in the gallbladder for too long. 4.Biliary tract infection, inflammation of the gallbladder wall, and its contraction function is diminished. 5.Some hemolytic diseases or hepatic sclerosis can also lead to gallbladder stones, which are mostly black stones. 6.Biliary stagnation caused by pregnancy and imbalance of the nervous system can also cause gallbladder stones. 7. Long-term fasting and intravenous nutrition can lead to bile stagnation in the gallbladder and stone formation. Clinical manifestations 1, gallbladder stones in the early stage usually about 60% of patients without obvious clinical manifestations, in the examination or perform other surgery on the upper abdomen and be found. Some of the single or multiple gallbladder stones exist freely in the gallbladder and are less likely to become lodged and rarely produce symptoms, which is called asymptomatic gallbladder stones. 3.Small stones in the gallbladder can be embedded in the neck of the gallbladder, causing clinical symptoms, especially when the gallbladder contracts after eating a fatty diet or due to position change during sleep, which can aggravate the symptoms. 4.When the gallstone is embedded in the neck of gallbladder, it causes acute obstruction, resulting in increased pressure in the gallbladder, and bile cannot be discharged through the neck of gallbladder and gallbladder duct, which causes clinical symptoms, usually manifested as biliary colic. Laparoscopic cholecystectomy] has become the “gold standard” procedure for the treatment of gallbladder stones, and is widely recognized by patients for its small trauma and quick recovery. If preoperative history, clinical manifestations or imaging confirm or highly suspect obstruction of the common bile duct, or if intraoperative lesions of the common bile duct are confirmed, open cholecystectomy is considered. Then open cholecystectomy and, if necessary, common bile duct exploration will be considered. Dietary care It is advisable to consume coarse grains, fresh vegetables, garlic, onions, mushrooms and fungus which can lower cholesterol. Eat vegetables rich in vitamin A or vitamin K: for example, cauliflower is rich in vitamin K. Other vegetables rich in vitamin A are: carrots, tomatoes, spinach, soybeans, green peas. Avoid high-fat foods, lard, fried foods, and pastries with lots of oil. Avoid spicy and stimulating condiments, such as chili, pepper, chili oil, five-spice powder, pepper, and spicy tofu. Avoid smoking, alcohol, coffee, strong tea, margarine, soft drinks, sugar products, chocolate.