Liquefied lipomatosis is an extremely rare disease with an unknown etiology, possibly related to excessive pancreatic secretion of amylase, pancreatic enzymes, and lipase. The disease can be treated with nonsteroidal anti-inflammatory drugs, glucocorticoids, and growth hormone-releasing inhibitory factor analogs.
Liquefied seborrhea, a specific type of nodular seborrhea, is extremely rare. Its main feature is the liquefaction and degeneration of subcutaneous nodules, on which the skin can be necrotic and ulcerated, with yellow or brown oily fluid discharge. Non-steroidal anti-inflammatory drugs (NSAIDs), glucocorticoids, immunosuppressants and growth hormone releasing inhibitor analogs can be given for treatment.
1. Non-steroidal anti-inflammatory drugs (NSAIDs) and glucocorticoids: When patients have high fever, joint symptoms and skin lesions, NSAIDs such as ibuprofen and celecoxib can be used under the guidance of a doctor to alleviate the joint symptoms and reduce the fever, and glucocorticoids such as hydrocortisone, methylprednisolone and dexamethasone can be used if necessary.
2. Growth hormone release inhibitory factor analogs: such as octreotide, the drug can inhibit both growth hormone secretion and gastric, intestinal and pancreatic secretion of biopeptides. Some studies have shown that after the treatment of liquefied seborrheic meningitis with growth hormone-releasing inhibitory factor analogs combined with glucocorticoids, the blood and urinary amylase can be gradually decreased, and the subcutaneous nodules can be subsided very quickly.
Patients with liquefied seborrheic meningitis are advised to go to the rheumatology and immunology departments of regular hospitals and follow the doctor’s instructions to standardize the diagnosis and treatment, and do not use medication on their own.