Outpatient clinics often see children with subconjunctival hemorrhage, or what parents think of as bleeding from the white eye, in the setting of fever. In cases of large subconjunctival hemorrhage, or a state of persistent conjunctival congestion in both eyes, local treatment of the eye should be accompanied by a consultation with internal medicine to rule out Kawasaki disease. Kawasaki disease, also known as cutaneous mucocutaneous lymph node syndrome (MCLS), is an acute febrile exanthematous pediatric disease with systemic vasculitis as the main pathology. Kawasaki disease was first reported in Japan in 1967, and its incidence has been increasing year by year, and has replaced rheumatic fever as the leading cause of acquired heart disease in children in China and some western countries. The etiology of the disease has not been clarified so far, and its diagnosis relies mainly on a group of clinical manifestations that appear during the course of the disease without a specific etiological basis. The disease is a vasculitis syndrome that occurs in children aged 2 to 4 years, with a prevalence in boys. In China, the disease is more frequent from July to September. Kawasaki disease needs to be ruled out if the child presents with persistent fever for 5 to 11 days or longer (2 weeks to 1 month), often with a temperature of 39°C or higher, ineffective antibiotic treatment, with cardiac damage, and a state of subconjunctival hemorrhage or congestion.