Gallbladder cancer is a gastrointestinal tumor with high malignancy. Gallbladder cancer is not surgically treatable at advanced stage and its survival period is short, usually 3-6 months. Gallbladder cancer is less sensitive to radiotherapy, gene targeted therapy, etc. There are no good measures to inhibit the metastasis and spread of cancer cells in the advanced stage of gallbladder cancer, and most of them can only support symptomatic treatment to relieve patients’ pain and improve their quality of life, so their survival period is about half a year. If patients with gallbladder cancer have serious complications, such as acute perforation of gallbladder, biliary bleeding, thus causing diffuse liver metastasis or hemorrhagic shock, it will accelerate the process of death of patients, which may occur within hours to days. Early detection, early diagnosis and early treatment of gallbladder cancer are very important to prolong patients’ survival. Therefore, for people with chronic atrophic cholecystitis, gallbladder adenoma and other high-risk groups, they should go to the gastroenterology department of the hospital regularly for review and treatment once abnormalities are detected.