Drinking calf soreness should be alert to the leg muscles have chronic injury, gout, liver and kidney dysfunction and other diseases. 1. Leg muscles have chronic injury: in the case of drinking alcohol, alcohol stimulation will make blood vessels dilated, which will easily lead to increased inflammation at the site of injury and calf soreness. 2. Gout: alcohol competes for the metabolic channels of blood uric acid and reduces uric acid excretion, uric acid will accumulate in the body, which may lead to the occurrence of gout and may lead to calf soreness. 3. Liver and kidney insufficiency: if you suffer from liver and kidney insufficiency, you can’t metabolize acetic acid better, alcohol is metabolized to acetic acid in the body, and acetic acid can enter the calf through the blood circulation, stimulating the calf nerves and causing the symptoms of calf soreness. The symptoms of calf soreness after drinking alcohol, should go to the regular hospital in time, clear cause, under the guidance of professional doctors to take targeted treatment.