The causes of calf soreness, leg shaking and hand shaking are mainly related to excessive fatigue, malnutrition, cold or neurological lesions. 1. Excessive fatigue: If the whole body is in a state of fatigue after heavy physical activities or strenuous exercise, the phenomenon of calf pain, leg shaking and hand shaking can occur. 2. Malnutrition: If the body has a long period of insufficient intake of nutrients, resulting in malnutrition, the body because of the lack of various trace elements and electrolytes are prone to produce calf pain accompanied by leg shaking and hand shaking symptoms, which in turn triggers motor dysfunction. 3. Cold: usually if you are in a cold environment for a long time, resulting in cold body, easy to appear limb shivering, accompanied by calf pain and other symptoms, appropriate warmth and rewarming after the symptoms will be relieved. 4. Neurological lesions: When there are neurological lesions, such as spinal cord injury or brain injury, it is easy to trigger neurological dysfunction, resulting in uncontrolled shaking of the limbs as well as soreness and other symptoms. Calf soreness leg shaking hand shaking symptoms such as rest, warmth after no apparent relief, should promptly consult a doctor, first identify the specific causes of the disease, under the guidance of professional physicians for targeted treatment.