Standing for a long time calf soreness consider muscle strain, lower extremity vascular valve closure insufficiency, lumbar disc herniation, diabetic vasculopathy, thrombotic vasculitis and other reasons. 1. Muscle strain: standing for a long time will cause calf muscle fatigue, lactic acid accumulation, soreness. 2. Lower extremity vascular valve closure insufficiency: vascular valve closure insufficiency can cause blood reflux, standing for a long time causes blood stagnation and soreness, swelling. 3. Lumbar intervertebral disc herniation: the load on the lumbar region increases when standing, and the herniated disc compresses the nerves, which can cause soreness in the calves. 4. Diabetic vasculopathy: diabetes causes narrowing of blood vessels and insufficient blood supply to the lower limbs, resulting in leg pain and coldness. 5. Thromboembolic vasculitis: lower extremity vasculopathy, reduced blood supply, lower extremity pain, resting pain, walking intermittent claudication. Standing for a long time calf soreness need to go to the hospital for further examination, clear diagnosis and then treatment.