How female adenocystitis is diagnosed and treated

  Adenocystitis is a chronic proliferative disease of the bladder mucosa, a special type of cystitis, and a common female disease in urology, mostly due to recurrent urinary tract infections. Clinical manifestations are urinary tract irritation symptoms such as urinary frequency, urinary urgency, urinary pain, and lower abdominal and perineal pain, microscopic hematuria, and some patients have carnal hematuria, accompanied by mental symptoms such as anxiety, tension, and insomnia. In recent years, with the clinical attention and the improvement of cystoscopy and pathological biopsy, the detection rate of adenoid cystitis has increased significantly.  Treatment of adenoidal cystitis should be mainly with targeted antibiotic therapy, but also with some drugs that target the symptoms of urinary frequency, pain and urgency. Due to long-term inflammatory stimulation, it causes changes in the bladder wall in the tissue structure, which makes drug treatment difficult. Malformation of the external urethra or other lesions in women is also one of the reasons why recurrent urinary tract infections are not easily cured, especially in middle-aged and elderly women. For female patients, attention should be paid to the presence of urethral meatus, hymenal umbrella, and malformation of the external urethra.  In recent years, through comprehensive examination, adenoidal cystitis that can be treated surgically, the choice of cystoscopic electrodesiccation, electrocautery surgery treatment, also has better results to reduce the pain caused by recurrent episodes.  Based on cystoscopy, adenoid cystitis is divided into four types: papillary, follicular or choroidal edema, chronic inflammatory, and mucosal without significant changes. The chronic inflammatory type and the type without significant mucosal changes are treated conservatively for 3-5 weeks after exclusion of obstruction and stone factors, and transurethral electrodesiccation or electrocautery is given after 3 months if symptoms do not improve or if the cystoscopic lesion persists. The papillary and follicular or choroidal edema types are treated with transurethral electrodesiccation and electrocautery.  The early stage of adenoid cystitis includes chronic inflammatory type and type without significant mucosal changes, which has a high incidence and should not be considered as precancerous lesions. However, if chronic irritants persist, advanced adenoid cystitis can develop, including the extensive intestinal epithelial metaplasia, papillomatous and intestinal adenoma types. Late stage adenocystitis has the potential for malignancy within a relatively short period of time and should be treated as a precancerous lesion and treated surgically aggressively. Early stage adenocystitis is not only not improved by local electrodes, but also worsens in some patients and has a high recurrence rate of lesions. The efficacy of conservative treatment for early mild cases is not significantly different from that of surgery. After conservative treatment, the lesions in the bladder may even develop in a positive direction, with the disappearance of follicle-like structures.  After electrodesiccation and electrocautery, bladder perfusion chemotherapy is mostly administered according to superficial bladder metastatic epithelial carcinoma. However, the perfusion of bladder chemotherapeutic drugs, patients’ postoperative bladder irritation symptoms do not improve significantly, some patients’ symptoms do not improve, and it increases the financial burden of patients and consumes more medical resources. Adenocystitis has the potential for malignancy, but the rate of malignancy is very low. Immediate postoperative bladder irrigation with a single dose of chemotherapy is sufficient without maintenance bladder irrigation chemotherapy. If bladder tumors are combined, they are treated as bladder tumors.