Running calf soreness can be caused by excessive muscle lactic acid production, inflammation, and muscle strain. Usually, static stretching, physical therapy and medication can be used. 1. Excessive secretion of muscle lactic acid: If the running time is relatively long and the calf muscles are overly fatigued, it is easy to cause excessive secretion of lactic acid, which will produce the symptom of calf soreness. It can be treated by static stretching, which can relax the muscles and help relieve the stiffness and pain of the body, thus relieving the symptoms of running calf soreness. 2. Inflammation: If there is myofasciitis in the calf area, the inflammatory reaction increases after running due to exercise, so it will trigger the symptoms of calf soreness. Ultrashort wave treatment can be used to promote blood circulation and strengthen the body’s metabolic rate, thus relieving the symptoms of running calf soreness. 3. Muscle strain: If you exert yourself too much when running, it may lead to the problem of soft tissue strain such as calf muscle, which is easy to appear the symptoms of running calf soreness. In the early stage, you can apply ice packs locally to reduce swelling and pain symptoms; at the same time, you can also cooperate with the use of ibuprofen extended-release capsules for treatment, which has analgesic, antipyretic and anti-inflammatory effects, thus relieving the symptoms of running calf soreness. If the patient running calf pain for a long time does not relieve, it is recommended to go to the hospital in time to find out the cause of the disease after targeted treatment.