There are many causes of calf pain in women, and it is more common to find lesions such as calf muscle strain, lower limb vascular lesions and neuropathy. There is no so-called quick relief method, and it is necessary to give general treatment, physical therapy such as hot compresses, medication such as ibuprofen, and surgical treatment such as saphenous vein ligation + repair, etc., according to the cause of the disease. 1. Calf muscle lesions: mostly seen in calf muscle strain, strain injury and lactic acid accumulation, etc., need to pay attention to rest, local cold compresses in the acute stage, and local hot compresses in the relieving stage. Soreness and pain can be given ibuprofen and other painkillers. 2. Lower extremity vascular lesions: such as varicose veins of the saphenous vein, deep vein thrombosis, etc. For lower extremity arteriovenous embolism and other need to give thrombolytic drugs, such as urokinase, etc., saphenous vein varicose elevation of the affected limb, wear compression stockings and other ways of treatment. In severe cases, saphenous vein ligation + repair or sclerotherapy can be given. 3. Neuropathy: such as lumbar disc herniation and other lumbar spine lesions, need to target the primary pathology treatment, such as ibuprofen and other painkillers, methylcobalamin and other nutritive drugs, conservative treatment is ineffective to give radiofrequency ablation and other surgical treatments. It is recommended that the patient go to the hospital, complete the auxiliary examination, in order to clarify the cause of the disease, the professional physician to give the appropriate treatment, the drugs need to be used under the guidance of a professional physician.