In general, fever and chills in gallstone disease are often caused by common bile duct stones. However, some patients with gallbladder stones may also develop these manifestations because of the combination of cholecystitis. In China, there is an increasing trend of gallbladder stone patients, which brings great harm to many patients, so for the sake of our health, we should know more about the symptoms of gallbladder stones. So what are the symptoms of gallbladder stones? Next, we will introduce the symptoms of gallbladder stones. The symptoms of gallbladder stones combined with cholecystitis are as follows: 1. fever and chills: fever is related to the degree of inflammation of the gallbladder. Gangrenous cholecystitis and purulent cholecystitis may have chills and high fever. 2, gastrointestinal symptoms: acute attacks of gallbladder stones, followed by abdominal pain often have nausea, vomiting and other gastrointestinal reactions. The vomit is mostly stomach contents, and the abdominal pain is not significantly relieved after vomiting. After the acute attack, there are often symptoms such as aversion to greasy food, abdominal distension and indigestion. 3, jaundice: some patients with gallbladder stones can develop transient jaundice, mostly after severe abdominal pain, and the jaundice is mild. Gallbladder stones with cholangitis, enlarged gallbladder pressing the common bile duct and causing partial obstruction, or due to infection causing transient damage to liver cells can cause jaundice. This is manifested as yellowing of the sclera of the eyes. More than 90% of biliary colic attacks are sudden, often after a full meal, overexertion or strenuous exercise. Stones tend to fall into the cystic duct when lying down, and some patients may have a sudden onset at night. In addition to severe pain, there is often restlessness, even tossing and turning, distraction, sweating, and pallor. Each attack can last from 10 minutes to several hours, and it often takes several days for the attack to resolve. Pain relief or disappearance indicates that the stone has retreated into the gallbladder, at which point other symptoms disappear.