Bile duct and gallbladder stone disease is a condition that occurs when stones in the human gallbladder and bile ducts obstruct the gallbladder and bile ducts, affecting bile excretion. Gallbladder and bile duct stone disease mostly develops due to physical factors, chronic inflammation, bile duct parasites, bile duct malformations, and poor bile drainage. The root cause of stone formation is the over-saturation of cholesterol in bile, the precipitation of relatively more unconjugated bilirubin in bile, and the relatively low amount of helper-soluble substances (such as bile acid salts) in bile, which produce insoluble polymorphs, or stones, by forming a foreign body core and combining with metal ions. In Chinese medicine, gallstone disease is thought to be caused by damp heat in the liver and gallbladder, which accumulates in the liver and gallbladder and injures the yin, leaving the evil in the liver and gallbladder and forming stones. Gallbladder and bile ducts can produce bile pigment stones, worm egg stones and hidden cholesterol stones on their own, or they can stay in the bile ducts when the stones are discharged from the liver. As the stones grow, they block the neck of the gallbladder and the bile ducts, preventing bile from draining smoothly. Bile is the main substance for digesting fats, and the absence of bile can cause indigestion, poor appetite, and lack of good taste. Gallstones are blocked in the gallbladder neck duct, which cannot be stored in the gallbladder and flow directly into the duodenum and reflux into the stomach, neutralizing gastric acid and causing indigestion. On the other hand, bile sludge in the bile duct, together with stones, causes smooth muscle tension and sphincter spasm of the bile duct and gallbladder, resulting in paroxysmal colic or distension. Sometimes even when the bile ducts are relaxed, the stones may irritate the bile ducts and cause vague pain. Even when eating fatty foods, the bile needs to be excreted in large quantities, so that the stones that normally do not block the neck of the gallbladder and the bile duct become active, blocking the bile excretion channel, and causing reflex pain in the bile duct. Excessive bile accumulates in the gallbladder and bile ducts, causing an increase in pressure in the hepatic ducts and bile ducts in the liver. The clinical manifestations of gallstone disease include paroxysmal colic or vague pain in the right epigastric region and right quadriplegic region, often involving the back of the right shoulder or the right scapular region, and the pain may occur suddenly or may be relieved quickly. It is accompanied by fever, chills, dyspepsia, loss of appetite, and sour mouth and bitterness. The attack is especially likely to occur when eating oily or fatty foods (fried, fatty meat, nourishing and greasy products). Emotionally restless, easily impatient or depressed. In severe cases, yellowing of the skin, white pearls of the eyes and nails, yellow and greasy tongue coating, red tongue texture and thin or slippery pulse are seen.