Mesenteric lymphadenitis in children is one of the common causes of abdominal pain in clinical children and is usually seen in children under 7 years of age. Treatment is primarily conservative and medical in nature. Mesenteric lymphadenitis in children often occurs during the course of an acute upper respiratory tract infection, or secondary to an acute upper respiratory tract infection, or can follow an intestinal infection. The main clinical manifestations are recurrent abdominal pain, which is irregular, paroxysmal, usually around the umbilicus, with fixed or unfixed pressure points, usually without rebound pain or abdominal muscle tension, occasionally accompanied by nausea, vomiting, diarrhea, and generally of short duration, relieving on its own, not related to eating, but occurring before or after eating, with variable nature and degree of pain. Ultrasound examination of the abdomen is usually indicated by enlarged mesenteric lymph nodes. It is important to differentiate clinically from acute appendicitis, intestinal parasites and other related diseases. After the diagnosis of mesenteric lymphadenitis is clear, most medical treatments are performed. The acute phase of bacterial infection resulting in mesenteric lymphadenitis can be treated with an effective anti-infective therapy of choice for about 1 week. If there is no sign of acute infection at present, oral Chinese medicine or external Chinese medicine treatment such as umbilical compress and tui-na can be used.