Case: Huanhuan, who lives in Yongdeng, Lanzhou, 1 year old, just after New Year’s Eve, started to have a high fever, and the routine blood test showed elevated white blood cells that exceeded the normal range, the doctor confirmed that it was a bacterial infection and gave him antibiotics. However, after a period of treatment, Huanhuan’s fever did not go down, and his body began to break out in a rash, the doctor thought the child was allergic to drugs, so he gave him a new antibiotic to use, although the rash went down, but after more than a week of treatment, the child still continued to have a high fever, sometimes even a high fever of 39 ℃ or more.” Huanhuan’s mother, Ms. Zhang, saw her son’s fever for more than 10 days, injections, medication, infusion, fever never go down, she rushed with her son from Yongdeng to the Department of Pediatrics of the Second Hospital of Landa. After learning that Huanhuan has had a high fever for more than 20 days and that many antibiotics have been ineffective, and that he also had a brief rash, she further affirmed her judgment after careful observation and finding that Huanhuan’s eyes were red and his mouth and lips were chapped. Subsequently, the physician arranged for Huan to have a cardiac ultrasound, which showed that Huan’s coronary arteries had become damaged and, ultimately, that Huan had Kawasaki disease. What is Kawasaki disease? Kawasaki disease is an acute febrile rash disease with systemic vascular inflammatory lesions mainly in the skin, mucous membranes and lymph nodes, also known as cutaneous mucosal lymph node syndrome. It is most commonly seen in young children between the ages of 8 months and 4 years, and occasionally in older children. The male to female ratio is 1.5:1, with more males than females. It can occur throughout the year, but most often occurs in the winter and spring. Kawasaki disease is often misdiagnosed because its symptoms are similar to those of the flu, and when this disease is misdiagnosed, it is extremely dangerous and may lead to acquired heart disease. The most typical symptom of this disease is fever, and a routine blood test will reveal an excessive total white blood cell count, so it is often treated as a bacterial cold, resulting in a delayed illness. What are the typical features of Kawasaki disease? A. Fever lasting for more than 5 days, with an average body temperature of 39-40 ℃, with fever or flaccid fever and ineffective antibiotic treatment. The conjunctiva of the eye is congested and there is no purulent discharge. Third, the lips and mouth are bright red, with dry cracking and bleeding, the oral mucosa is diffusely congested, and the tongue papillae are obvious, protruding and congested, resembling a strawberry-like tongue. The hands and feet are hard and swollen in the early stage, with membranous peeling in the later stage. V. Polymorphic rash on the trunk, which may appear as diffuse erythema, or scarlet fever-like rash without blistering crust. The skin around the anus is red and peeling. Lymph nodes in the neck are enlarged, unilateral or bilateral, with tenderness, not red on the surface, not purulent, and often transient. [Parental care precautions] Parents of children with Kawasaki disease should pay attention to dietary adjustments: a liquid or semi-liquid diet high in calories, protein and vitamins, avoiding raw, hard, overheated, spicy and irritating foods. Children with Kawasaki disease should also pay attention to regular outpatient follow-up after discharge. Children and their families need to actively cooperate with the doctor’s treatment; insist on regular outpatient follow-up, generally requiring review of electrocardiogram, echocardiogram, blood routine and coagulation function 1 month, 2 months, 3 months, 6 months, 1 year, 1.5 years and 2 years after discharge, and adjust the medication accordingly according to the child’s clinical symptoms and examination results; in taking If bleeding symptoms of epistaxis occur during the period of aspirin, be sure to come to the hospital for follow-up.