Kawasaki disease develops mainly in infants and young children and is also known as mucocutaneous lymph node syndrome. Children infected with Kawasaki disease will develop fever at the earliest stage, and will also have symptoms of eye, lip, hand, foot, and skin lesions that require medical attention for diagnosis: 1. fever: the earliest and more typical symptom, children with Kawasaki disease will develop fever of unknown origin after infection, with body temperature up to 39-40°C, fluctuating more than 2°C within 24 hours, and generally for more than 5 days or longer. 2. Eye symptoms: children with Kawasaki disease may have congestion of the bulbar conjunctiva for 3-4 days without purulent discharge, and the edema and congestion may disappear after the fever subsides; 3. Skin manifestations: polymorphic erythema and scarlet fever-like rash often appear in the first week of Kawasaki disease infection, and localized skin reddening and peeling can be observed around the anus. In addition, the child may also have some non-specific signs and symptoms, such as cough, abdominal pain, bloating, diarrhea, etc. If early anti-infective treatment is ineffective and some of the clinical manifestations of Kawasaki disease are present, and auxiliary tests such as ultrasensitive C-reactive protein are abnormal, the child should be promptly considered as a suspected case and attention should be paid to exclude other diseases.