Treatment options vary depending on the cause: muscular origin, such as soreness in the calves after exercise, often caused by lactic acid buildup, will gradually subside. You can also suspend exercise, rest and receive physical therapy, etc. Usually, it is important to warm up before exercise, to exercise regularly and in appropriate amounts, and to avoid excessive exercise. Neurogenic and vascular origin are treated according to the severity of the primary disease, and severe cases require surgical intervention.