The symptoms of lipofuscinosis are not well understood and many people have never heard of lipofuscinosis, which is actually a very common medical condition. What are the manifestations of lipofuscinosis? 1. Lipofuscinosis, as we can currently understand it, is characterized by general discomfort, arthralgia, fever, and subcutaneous nodules. The nodular lipofuscinosis can be divided into cutaneous and systemic cutaneous types depending on the location, and the lesions will only invade the subcutaneous fatty tissue structures without harming the accumulated internal organs. The skin of seborrhea is dark red, without any edema, and the subcutaneous nodules are slightly above the skin surface, and its texture is relatively firm, which can be spontaneously painful or obvious when touched. After the nodules have subsided, the local skin will show varying degrees of depression and pigmentation, which is the residual atrophic scar due to fat atrophy and fibrosis, some nodules can disappear and break up on their own, but most of them will leave scars. Lipofuscinosis may be an unfamiliar condition to many people, but if we are not properly informed and familiar with its possible causes, this will not bring any benefit to our body and we should understand in detail to do comprehensive prevention work.