If the diagnosis is not confirmed by palpation, percussion can be used to check for enlargement of the splenic turbinate. (The normal splenic turbinate is between the 9th and 11th ribs in the left axillary midline; it is 4-7 cm wide and does not exceed the anterior axillary line in front. When palpation reveals splenomegaly or even mega-splenomegaly, attention should be paid to the degree and quality of splenomegaly, as well as to the presence of other accompanying signs. The physical examination of mega-splenomegaly is related to the disease. 1. Mild splenomegaly Mild splenomegaly is defined as having the lower edge of the card 2-3 cm below the rib cage during deep inspiration. It can be seen in certain viral infections, bacterial infections, rickettsial infections, early schistosomiasis, congestive heart failure, cirrhotic portal hypertension, and Hodgkin’s disease. Juvenile rheumatoid arthritis fire, systemic lupus erythematosus, tropical eosinophilia, idiopathic thrombocytopenic purpura, etc. 2. Moderate splenomegaly The lower margin is moderately enlarged from 3 cm below the rib cage to the flat umbilicus. It can be seen in acute granulocytic leukemia, acute lymphoblastic leukemia, chronic hemolytic anemia, infectious mononucleosis, rickets, splenic amyloidosis, malignant lymphoma, Niemann’s disease, etc. 3. Extreme splenomegaly is defined as extreme splenomegaly or giant spleen when the lower edge of the spleen exceeds below the level of the umbilicus. It can be seen in chronic granulocytic leukemia, chronic malaria, advanced schistosomiasis, zoster disease, myelofibrosis, true erythrocytosis, thalassemia, Gaucher disease, etc.