The causes of sore calves at night in bed can be divided into two types.
One is the physiological soreness that occurs as a result of muscle tension due to a daytime job that requires prolonged standing or a high level of exercise during the day, which is generally self-healing and does not require treatment.
The other is soreness due to long-term muscle damage caused by paroxysmal muscle spasms at night, which need to be managed and treated promptly for the muscle spasms.