Many people experience leg pain once they enter menopause, and there are two common reasons for this: First, bone loss due to hormonal changes in the body after entering menopause, and bone loss can gradually worsen and cause osteoporosis. The clinical manifestation of osteoporosis is the appearance of leg pain, as well as general joint pain and coldness. Second, there are also common causes of osteoarthritis of the knee joint. With age, knee degeneration, cartilage degeneration, soft tissue degeneration around the knee joint, and osteophytes, it is easy to cause knee joint pain. The pain can recur and even get progressively worse, and in severe cases there may be symptoms of knee deformity and restricted movement. Once leg pain occurs, it is important to clarify what is causing it, whether it is caused by osteoporosis or by osteoarthritis of the knee joint. Once you find the cause, you can target it and treat it with half the effort. If it is caused by osteoporosis, anti-osteoporosis treatment, along with anti-inflammatory and analgesic drugs, can provide significant relief. If it is osteoarthritis of the knee joint, you can use anti-inflammatory and analgesic drugs, and at the same time use drugs for osteoarthritis, such as ammonia, chondroitin, or joint cavity injection of sodium vitrate can have a significant improvement effect on leg pain.