What are the diagnostic criteria for Kawasaki disease

  Kawasaki disease (Kawasaki disease), also known as cutaneous mucosal lymph node syndrome, is an acute febrile exanthematous pediatric disease characterized by systemic vasculitis.  The Japanese MCLS Research Committee (1984) suggested that the diagnosis of this disease should be determined by meeting at least five of the following six major clinical symptoms: 1. fever of unknown origin lasting 5 days or more; 2. bilateral conjunctival congestion; 3. diffuse congestion of the mucous membranes of the mouth and pharynx, red and dry lips, and a prune tongue; 4. stiff swelling of the hands and feet and redness of the palms and plantars at the beginning of the disease, as well as the appearance of the end of the fingers and toes during the recovery period; 5. 5. Polymorphic erythema of the trunk without blisters and crusts; 6. Non-suppurative swelling of the cervical lymph nodes with a diameter of 1.5 cm or larger. However, if a coronary artery aneurysm or dilatation is detected by 2D echocardiography or coronary angiography, a positive diagnosis is confirmed by the four main symptoms.  In recent years, an increase in incomplete or atypical cases has been reported in about 10% to 20% of cases. Only 2 to 3 major symptoms are present, but there is a typical coronary artery lesion. It occurs mostly in infants. The incidence of coronary aneurysms is similar in typical and atypical cases. Echocardiography should be done as soon as possible when Kawasaki disease is suspected.