The answer is no. Each woman has about 2 million follicles at birth, most of which gradually degenerate during childhood, and by puberty there are about 200,000 to 400,000 follicles left in both ovaries. During the late luteal phase of the previous menstrual cycle and the early follicular phase of the current menstrual cycle, a group of sinus follicles (about 3-11) in each ovary will enter the growth trajectory together with the action of follicle stimulating hormone (FSH), while the other follicles will be atretic. The growth of follicles after recruitment depends mainly on gonadotropins, especially follicle stimulating hormone (FSH), and follicles can only continue to grow when FSH levels reach or exceed a certain threshold. In a natural cycle, around day 5-7 of the menstrual cycle, the one follicle with the lowest FSH threshold, i.e. the one most sensitive to FSH, will preferentially develop into the dominant follicle, while the other follicles will gradually atrophy due to their low sensitivity to FSH. There can be more than one follicle in a cycle, but usually only one follicle is seen to mature and ovulate occasionally, and this follicle is often referred to as the dominant follicle. In an ovulation cycle, the doctor will start applying ovulatory drugs, most commonly exogenous FSH, before the appearance of the dominant follicle, usually on the 2nd to 4th day of menstruation, to encourage the growth of the follicles that would otherwise be atretic, but the primordial follicles that are not collected during the cycle will remain quiescent and will not be affected. Therefore, ovulation promotion does not prematurely deplete the ovarian stock of follicles, but rather is a form of “waste utilization” that allows the follicles that would otherwise be atretic to develop and mature together, obtaining as many mature eggs as possible in one cycle to obtain as many quality embryos as possible.