The voice microsurgery technique is performed under microscopic or endoscopic guidance with the application of microscopic instruments or laser to maximize the preservation of the basic tissue outcome and function of the vocal folds. The surgery seeks to maintain the integrity of the vocal cord epithelium and minimize surgical trauma damage. The main scope of application includes: benign proliferative lesions, laryngeal papilloma, amyloidosis, pre-cancerous lesions and early vocal fold cancer, laryngeal stenosis, bilateral vocal fold paralysis, vocal fold scar, vocal fold sulcus, etc. Department of Otolaryngology, The Third Affiliated Hospital of Sun Yat-sen University Ye Jin Surgery Microlaryngoscopy Application Microlaryngoscopy is a laryngeal surgery performed with specially designed microsurgical instruments under the observation of an operating microscope through a specially designed supporting laryngoscope. The surgery is performed under a binocular surgical microscope with a magnification of 6-40 times, and the surgeon uses two hands to operate simultaneously to preserve the unique layered tissue structure of the vocal cords to the maximum extent possible, which is truly microscopic and minimally invasive surgery. Since the birth of the CO2 laser in 1965, its application in the medical field has become increasingly mature, greatly breaking through the limitations of traditional surgery. CO2 laser has unique advantages in voice microsurgery, and it is superior to traditional surgery in that it has: (1) less damage, no neck incision or tracheotomy; (2) less bleeding and clear field; (3) high accuracy and good functional preservation; and (4) faster healing and scarring. ④Fast healing, small scar, less infection; ⑤Short operation time, less patient pain and other advantages. CO2 laser can preserve the articulatory structure and function to the greatest extent and restore good articulatory function for benign proliferative lesions (cysts, polyps, Renk’s edema), benign laryngeal tumors (papilloma, hemangioma, fibroma) and laryngeal amyloidosis. It has a high cure rate for early laryngeal cancer. It can not only remove the lesion, stop the malignant development trend and improve the symptoms, but also preserve the laryngeal function to the greatest extent, and the local control rate and 5-year survival rate are the same as those of open surgery. Compared with traditional laryngeal cancer surgery, it has many advantages: (1) rapid surgery, shortening treatment time and cost; (2) low complications and no tracheotomy; (3) good pronunciation can still be obtained after surgery, and patients’ quality of life is improved compared with that before surgery; (4) laser treatment does not exclude other treatments, and even if the lesion recurs, there are still opportunities to choose other treatments.