There is no such thing as the fastest way to relieve calf pain. It needs to be analyzed according to the cause, mainly related to calf muscle fatigue, aseptic inflammation or strains, etc. Generally, you can choose physical factor therapy, medication or exercise therapy. 1. Calf muscle fatigue: usually if you often weight-bearing exercise, frequent contraction of the calf muscles, resulting in the accumulation of local lactic acid, easy to produce a feeling of fatigue, thus appearing symptoms of calf soreness, you can generally choose to local intermediate frequency electrical stimulation with the fascia knife and other methods for relief. 2. Aseptic inflammation: If there is aseptic inflammation in the calf area, such as fasciitis, etc., the stimulation of inflammation is easy to produce symptoms of soreness, you can consider using medication, such as taking meloxicam or celecoxib, etc., which can play a role in anti-inflammatory and analgesic effect. 3. Strain: usually improper exercise or excessive force caused by the calf part of the muscle soft tissue strain, easy to produce the feeling of pain, you can consider through the exercise treatment method to relieve, such as the local muscle soft tissue stretching, with muscle strength training methods, help to speed up the recovery. When symptoms of calf soreness occur, you also need to consider whether there are varicose veins, arterial embolism and gouty, osteoarthritis and other conditions. If the symptoms worsen or have not been relieved for a long time, it is recommended to go to the orthopedic department for consultation and targeted treatment under the guidance of a professional physician, so as to prevent the later impact on the motor function of the calf.