Headache refers specifically to pain in the region of the vault of the head! It mostly has a general spectrum of disease as its cause! But a few headaches have a critical emergency etiology! Its key is mostly combined with high fever, vomiting, twitching, neck stiffness, altered consciousness, etc.! There are more than one hundred and thirty causes in nine categories! Its diagnosis and treatment are mostly in the form of exclusion! The diagnosis and treatment of headache is mainly based on a detailed history and the involvement of the damaged anatomy of the head! The final outcome of the treatment of headache is mostly good!