OBJECTIVE: To evaluate the diagnostic value of echocardiography in the diagnosis of Kawasaki disease invading the coronary arteries and causing coronary aneurysm formation. MATERIALS AND METHODS: The echocardiographic findings of 175 children with Kawasaki disease from 2000-01 to 2005-12 were retrospectively analyzed, including the location, course and internal diameter size of the coronary arteries and the ratio of the internal diameter of the coronary arteries to that of the aorta, and the diagnosis of coronary artery aneurysm was made with reference to the four-level classification of KATO coronary angiography. RESULTS: The ultrasound images of all children were clear, and the short-axis view of the parasternal aorta and the apical five-chamber view showing the left and right coronary artery trunks were the best. 4 cases were consistent with the diagnosis of aneurysm, of which 3 cases were grade 2 and 1 case was grade 3. Conclusion: Echocardiography can clearly show the internal diameter and morphology of coronary arteries and early detection of coronary artery aneurysm due to Kawasaki disease, which can help the diagnosis and treatment of Kawasaki disease and prognosis Weiqing Yao, Department of Pediatric Internal Medicine, Shanghai Xinhua Hospital. Kawasaki disease, also known as cutaneous mucocutaneous lymphatic syndrome, is a self-limiting vasculitis syndrome of unknown origin, an acute febrile rash disease with systemic vasculature as the main lesion, which can involve the heart, kidney, gastrointestinal and skin. In some patients, the lesions may invade the coronary arteries, causing coronary artery dilation and even coronary artery aneurysm formation. It has been reported in the literature that “2D echocardiography is valuable in the diagnosis of Kawasaki disease with coronary artery invasion and coronary aneurysm formation. In this study, we analyzed the echocardiographic findings of children with Kawasaki disease in recent years to investigate the value of echocardiography in the diagnosis of coronary artery aneurysms due to Kawasaki disease.