How long can malignant liposarcoma live depends on the location, volume and size of the liposarcoma, as well as the patient’s treatment. 1. If the malignant liposarcoma is located on the body surface and has a small volume, a complete resection of the tumor can be performed, along with local radiotherapy treatment. In this case, the patient’s prognosis is often better due to complete resection of the tumor lesion, and the survival time of 5-10 years can be more than 60%. 2. If the malignant liposarcoma is larger in size and located in the abdominal cavity, it has invaded important blood vessels, nerves and organs. In this case, the complete resection of the tumor is not possible, and even if radiotherapy or chemotherapy treatment is carried out, the effect is often unsatisfactory, and the patient’s survival is usually 3-6 months.