Palmoplantar pustulosis does not usually progress to the whole body. Palmoplantar pustulosis lesions are usually limited to the palms of the hands and foot metatarsals, symmetrically distributed, the palms of the hands preferably in the small pisiforms and pisiforms, which can be extended to the palms, dorsum of the hands, fingers and other parts of the palm, the foot metatarsals preferably in the mid-plantar and the medial side of the metatarsals. The lesions are small pustules that appear in batches on the basis of erythema, and after 1~2 weeks, the pustules rupture, crust, and flake off, and new pustules appear under the scales, which are sometimes mild and sometimes severe, and do not heal for a long time, and can often involve the nails. Palmoplantar pustulosis is a kind of psoriasis, there are other types of psoriasis, such as psoriasis has progressed to develop into a type of systemic psoriasis, at this time there will be systemic symptoms. If you find palmoplantar pustulosis, you need to go to the hospital as soon as possible, and the doctor will make a specific diagnosis and treatment plan, so as not to delay the condition.