The treatment of palmoplantar pustulosis is more difficult, and the disease is prone to recurrence, the treatment can be selected according to the severity of the patient’s condition, as follows: 1, the condition is mild: you can routinely choose to take oral anti-inflammatory treatment with clearing and detoxifying herbs combined with compound glycyrrhizin, and locally apply strong hormonal creams, such as halomethasone cream, and then you can combine narrow-spectrum ultraviolet radiation treatment, which has the effect of inhibiting the immune response, anti-inflammation, etc. 2, the disease is more serious: patients need to systematically take oral drugs to control the disease, often choose such as Avion, which has the role of inhibiting epidermal overproliferation, regulation of immunity, etc., can also choose immune preparations such as cyclosporine oral to control the disease. Palmoplantar pustulosis is a kind of pustular psoriasis, which mostly occurs in the palms of hands and toes, and severe patients can also be accompanied by joint pain.