Within an hour after ejaculation, the original jelly or clot-like semen will turn into a thin, flowing liquid, and this process is the liquefaction of sperm. If the semen is still jelly-like for more than 60 minutes, it is called semen non-liquefaction which can affect conception. The main cause of semen non-liquefaction is due to prostatitis or a lack of some specific enzymes. Only when the sperm is liquefied into a thin liquid can it swim better in the female vagina so that it can meet the egg and form a fertilized egg. If the semen is not liquefied, it can be seen under the microscope that the sperm are agglomerated into a mass and cannot move or can only move slowly. Furthermore, the lack of liquefaction of semen can cause the movement of sperm in the reproductive tract to be significantly impeded, and it is impossible for the sperm to move up into the cervical canal, the uterine cavity and the fallopian tubes to combine with the egg, making the data impaired. The reason why semen liquefies and the fibrinolytic enzymes contained in the prostate fluid has a lot to do with it. If inflammation occurs in the prostate gland it can cause a decrease in the amount of natural enzymes in the prostate fluid, which can lead to semen not liquefying. This is a very important reason why semen does not liquefy. After having seminal vesiculitis, it can cause too much coagulation factor or too little liquefaction factor in the semen and thus semen does not liquefy. In addition, malignant tumors of the ascending system are also common factors that lead to semen non-liquefaction in men. It is a common factor that causes male infertility, so you need to go to the hospital to have a relevant examination after this situation, so that the cause can be clarified and treated in time to avoid infertility.