After ejaculation, semen becomes jelly-like (this process facilitates the accumulation of semen in the vagina, especially in the location of the posterior vaginal vault, to prevent semen from flowing out of the vagina after ejaculation in a clear and dilute state), and after about 5 to 10 minutes, semen starts to liquefy, which facilitates the movement of sperm and conception. Normally, semen will be completely liquefied within 30 minutes. If semen is still not liquefied after more than 60 minutes, it is called semen non-liquefaction. As the semen does not liquefy, it restricts the sperm from swimming and some other sperm agglutination (sperm head touching head, head touching tail, tail touching tail) will occur, thus preventing the sperm from passing through the cervix to the fallopian tube waiting for the egg there to unite, leading to infertility. This is the most common type of seminal plasma abnormality. What causes can lead to semen non-liquidity? 1. Problems with the prostate and seminal vesicle glands The secretion of the seminal vesicle gland causes semen to coagulate, while the secretion of liquefaction factors and other enzymes from the prostate gland causes semen to liquefy, both of which together regulate the coagulation and liquefaction of semen. If the function of these two glands is abnormal, it can lead to semen non-liquefaction. Much of the current clinical research has focused on the prostate gland, which is thought to secrete enzymes with reduced activity, thus creating an imbalance between liquefaction and coagulation factors. The most common cause is chronic prostatitis. 2, the influence of endocrine hormones The formation and liquefaction of semen clots is influenced by testosterone, which promotes the secretion of the gonads. A decrease in testosterone from any cause can cause a decrease in the secretory function of the prostate gland, resulting in semen non-liquefaction. What tests are required? 1. Semen routine is necessary to rule out large viscous semen due to long term absence of semen discharge. 2.Microbial, mycoplasma and chlamydia cultures of semen or prostate fluid: infections of the reproductive tract need to be ruled out 3.Anti-sperm antibodies: immune factors, which can lead to agglutination of sperm, therefore need to be ruled out. 4. Sex hormones: to know the level of testosterone. The treatment idea: semen indigestion accounts for about 10% of male infertility, and is also a difficult point of treatment because there is no specific medicine. Therefore, its treatment is not short and fast, and its treatment cycle is relatively long. During the course of treatment, the woman’s condition needs to be evaluated. Because it is difficult to completely improve the treatment of seminal fluid indigestion, but it is possible to promote pregnancy by helping liquefaction with medication and other drugs, and to observe the treatment while it is being carried out. Semen indeficiency is an advantage of TCM treatment. Chinese medicine treatment by nourishing Yin and clearing heat can often help liquefaction and promote the swimming of sperm to help pregnancy. For patients with symptoms of prostatitis, acupuncture can be used to increase the effectiveness of treatment. For those with inflammation of the sexual reproductive tract and low testosterone, targeted treatment is needed. Anti-infection and testosterone supplementation takes relatively long time.